Leukemia

Leukemia is the type of cancer which begin in bone marrow’s stem cell and is the cancer of white blood cells. It is characterized by the abnormal increase of immature white blood cells. Although the cause of leukemia is unknown but there are many risk factors which are associated with leukemia. They are like exposure to intense radiation, several viruses like human T-Cell virus, exposure to certain chemicals, etc. Broadly leukemia is divided into two types, namely Acute and Chronic. In acute leukemia immature blood cells increase rapidly making bone marrow unable to produce new blood cells. Whereas in chronic leukemia, relatively mature blood cells are increased abnormally exceeding the normal white blood cell count.

Signs and Symptoms: +

Main symptoms of leukemia include,

  • Tiredness
  • Anaemia
  • Repeated body infections
  • Increased bleeding and bruising
  • Headaches
  • Skin rash
  • Vomiting
  • Chest pain
  • Enlarged lymph glands
  • Fever
  • Night sweats
  • Unexplained weight loss
  • Discomfort and swelling in the abdomen

General diagnostic tests suggested:+

Many times doctors diagnose leukemia just after simple routine blood test by complete blood count of white blood cells, red blood cells and platelets.

Test available at Oncquest:+

  • Test: Leukemia Screening Panel * CBC * Peripheral Smear * Slide Review * Cytochemistry (if required)

The technique used: Review by Pathologist for Presence of Malignant cells & Staining by Special Stains (if required)
Sample required: Submit 5 – 6 ml. Whole blood or Bone Marrow Aspirate.
Run days at section: Everyday
Reported on: 3rd Working Day if received before 1200 Hrs.

  • Test: Acute Leukemia Comprehensive Diagnostic Panel

 

The technique used: Flow Cytometry
Sample required: 7 – 8 ml. Whole Blood OR 3-4 ml of bone marrow.
Run days at section: Daily if received before 1400 Hrs.
Reported on: Next Working Day of Receipt of Specimen

  • Test: Acute Leukemia Basic Lineage (T, B, Myeloid) Panel

The technique used: Flow Cytometry
Sample required: 4 – 5 ml. Heparin anticoagulated Whole Blood OR 3 – 4 ml. of bone marrow.
Run days at section: Daily if received before 1400 Hrs.
Reported on: Next Working Day of Receipt of Specimen

  • Test: Acute Lymphoblastic Leukemia (ALL) Characterization Panel

The technique used: Flow Cytometry
Sample required: 5 – 6 ml. Whole Blood.
Run days at section: Daily if received before 1400 Hrs.
Reported on: Next Working Day of Receipt of Specimen

  • Test: B – Cell Acute Lymphoblastic Leukemia, (B – ALL) Characterization Panel

The technique used: Flow Cytometry
Sample required: 5 – 6 ml. Whole Blood Or 3 – 4 ml. of bone marrow.
Run days at section: Daily if received before 1400 Hrs.
Reported on: Next Working Day of Receipt of Specimen

  • Test: T – Cell Acute Lymphoblastic Leukemia, (T – ALL) Characterization Panel

The technique used: Flow Cytometry
Sample required: 4 – 5 ml. Whole Blood Or 3 – 4 ml. of bone marrow. Run days at section: Daily if received before 1400 Hrs.
Reported on: Next Working Day of Receipt of Specimen

  • Test: Acute Myeloid Leukemia (AML) Characterization Panel

The technique used: Flow Cytometry
Sample required: 4 – 5 ml. Whole Blood Or 3 – 4 ml. of bone marrow. Run days at section: Daily if received before 1400 Hrs.
Reported on: Next Working Day of Receipt of Specimen

  • Test: Acute Leukemia Comprehensive Diagnostic Panel and Karyotyping

The technique used: Flow Cytometry & Cytogenetics
Sample required: 7 – 8 ml whole blood /4 – 5 ml bone marrow  AND 2 ml of heparinized bone marrow for Karyotyping.
Run days at section: Everyday
Reported on: Flow Cytometry- Next Working Day if received before 1400 Hrs. Cytogenetics- 15 Working Days

  • Test: Acute Leukemia Basic Lineage (T, B or Myeloid) Diagnostic Panel and Karyotyping

The technique used: Flow Cytometry & Cytogenetics
Sample required: 4 – 5 ml whole blood /2 – 3 ml bone marrow AND 2 ml of heparinized bone marrow for Karyotyping.
Run days at section: Everyday
Reported on: Flow Cytometry- Next Working Day if received before 1400 Hrs. Cytogenetics- 15 Working Days

  • Test: Acute Lymphoblastic Leukemia Panel (ALL Characterization) and Karyotyping

The technique used: Flow Cytometry & Cytogenetics
Sample required: 7 – 8 ml whole blood /4 – 5 ml bone marrow AND 2 ml of heparinized bone marrow for Karyotyping. Run days at section: Everyday

Reported on: Flow Cytometry- Next Working Day if received before 1400 Hrs. Cytogenetics- 15 Working Days