Hepatitis

Hepatitis is the medical condition referring to the inflammation of the liver resulting in the swelling of liver. Hepatitis occurs usually due to the viral infection, but there are also different reasons associated with it like liver injury caused by toxin, bacterial infection, sometimes attack of one’s own immune system on liver and causing autoimmune hepatitis, exposure of the liver to harmful substances like alcohol, smoke, drugs, certain medications, some industrial organic solvents, etc. Acute hepatitis may pass without causing any permanent damage to the liver while chronic hepatitis may lead serious damages to the liver like liver failure. The most common type to hepatitis is Hepatitis A, Hepatitis B, Hepatitis C and lesser common types are Hepatitis D and Hepatitis E.

Signs and Symptoms: +

Sign and symptoms of hepatitis may include some or all of the below mentioned conditions:

  • Jaundice
  • Fever
  • Yellowing of skin and eyes
  • Enlarged liver
  • Abdominal pain
  • Poor appetite
  • Vomiting
  • Nausea
  • Fatigue
  • Change in color of urine
  • Muscular and joint pain
  • Diarrhea
  • Abnormal menstruation

General diagnostic tests suggested:+

There are several laboratory tests which your physician can go through to diagnose and monitor hepatitis, including,

  • Liver function tests: These tests are carried out to examine the proper functioning of the liver and also other varied function for which liver is held responsible. This test examines the level of liver protein and bilirubin, level of liver enzymes, transaminases, etc.
  • Liver protein and hepatitis tests: These tests are carried out to check the level of prothrombin, albumin and immunoglobulins in the liver.
  • Liver biopsy: This test is done to check for liver damage. This test is considered to give most accurate results out of all the tests.
  • Abdominal ultrasound
  • Specific tests for detecting the different type of hepatitis:
  • Hepatitis A: Anti-HAV IgM, Anti-HAV Total
  • Hepatitis B: HBsAg, HBsAg Confirmatory, Anti-HBs, Anti-HBc Total, Anti-HBc IgM, HBeAg, Anti-HBe
  • Hepatitis C: HCV

Test available at Oncquest:

  • Test: HAV, IgG Antibody, Serum Antibody to Hepatitis A, IgG

The technique used: Microparticle Enzyme Immunoassay
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 12:00 p.m.
Reported on: 5th Working Day after 7:00 p.m

  • Test: HAV, IgG Antibody, Serum Antibody to Hepatitis A, IgM

The technique used: CMIA
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HBc IgM/ANTI HB CORE IgM Antibody to Hepatitis B core IgM

The technique used: CMIA
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HBc Totao/ANTI HB Core Total Antibody to Hepatitis B core Total

The technique used: CMIA
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HBsAb /ANTI Hbs, Serum Antibody to Hepatitis B Surface Antigen

The technique used: CMIA
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HBsAg (Hepatitis B Surface Antigen) Australia Antigen Qualitative (HBsAg spot for screening only), Serum

The technique used: Rapid Card Test
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HBe Ab/ANTI – Hbe, Serum Hepatitis B Envelope Antibody, Serum

The technique used: CMIA
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HBeAg, Serum Hepatitis B Envelope Antigen, Serum

The technique used: CMIA
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HCV (Hepatitis C Antibody) Qualitative (HCV spot for screening only), Serum

The technique used: Rapid Card Test
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Monday if received before 2:00 p.m.
Reported on: Same Day by 7:00 p.m

  • Test: HCV IgM/ANTI HCV IgM, Serum Hepatitis C Virus IgM Antibody, Serum

The technique used: Enzyme Immunoassay
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Tuesday /Thursday /Saturday if received before 12:00 p.m.
Reported on: 5th Working Day by 7:00 p.m

  • Test: HEV IgM/ANTI HEV IgM, Serum Hepatituis E Virus Antibody IgM, Serum

The technique used: ELISA (Enzyme Linked Immunosorbent assay)
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Daily if received before 2:00 p.m
Reported on: Next Working Day by 7:00 p.m

  • Test: HEV IgG/ANTI HEV IgG, Serum Hepatitis E Virus Antibody IgG, Serum

The technique used: Enzyme Immunoassay
Sample required: 2 ml. (1 ml. Minimum) Serum.
Run days at section: Tuesday/Friday if received before 12:00 p.m.
Reported on: 4th Working Day by 7:00 p.m

  • Test: Hepatitis – B Profile Comprehensive Includes *HBsAg *Anti HBs *HBeAg *Anti – Hbe *HB core IgM Antibody *HB core Total Antibody

Sample required: 3 ml. (2 ml. Minimum) Serum.
Special Instruction: 12 -14 Hrs. (Overnight) fasting is preferred. Specify clinical history on test requisition form.
Run days at section: Daily if received before 2:00 p.m.
Reported on: Next Working Day by 7:00 p.m

  • Test: Hepatitis Aqute, Serum *Anti HAV IgM * HBsAg *HBeAg *Anti HCV IgM *Anti HBcore IgM Antibody *Anti HEV IgM

Sample required: 3 ml. (2 ml. Minimum) Serum.
Special Instruction: 12 -14 Hrs. (Overnight) fasting is preferred. Specify clinical history on test requisition form.
Run days at section: Daily if received before 12:00 p.m.
Reported on: 6th Working Day by 7:00 p.m

  • Test: Hepatitis AQUCHECK, Serum *Anti HAV IgM * HBsAg *HBeAg *Anti HBcore IgM *Anti HCV IgM *Anti HEV IgM *SGOT *SGPT *Bilirubin (Total) *Bilirubin (Direct) *Bilirubin (Indirect)

Sample required: 3 ml. (2 ml. Minimum) Serum.
Special Instruction: 12 -14 Hrs. (Overnight) fasting is preferred. Specify clinical history on test requisition form.
Run days at section: Daily if received before 12:00 p.m.
Reported on: 6th Working Day by 7:00 p.m

  • Test: Hepatitis Autoimmune Profile *Anti LKM – 1 *Anti Smooth Muscle Antibody *ANCA

The technique used: IFA (Immunofluorescence Assays)
Sample required: 3 ml. (2 ml. Minimum) Serum.
Special Instruction: 12 -14 Hrs. (Overnight) fasting is preferred. Specify clinical history on test requisition form.
Run days at section: Monday/Wednesday / Friday if received before 12:00 p.m.
Reported on: 8th Working Day by 7:00 p.m

  • Test: Tracq – B HBV DNA Quantitative PCR

The technique used: Real Time PCR (Quantitative)
Sample required: 4 – 5 ml. Whole blood.
Run days at section: Alternate day
Reported on: 3rd Working day if received by 1400 Hrs

  • Test: HBV Scan HBV DNA Quantitative PCR & HBsAg, HBeAg and Anti HBe Antibody Combo Panel

The technique used: Real Time RT- PCR (Quantitative) & CLIA
Sample required: 4 – 5 ml. Whole blood.
Run days at section: FOR PCR: Alternate day, FOR CLIA: Everyday
Reported on: 3rd Working day if received by 1400 Hrs

  • Test: HBV Ampliq HBV DNA Qualitative PCR

The technique used: Real Time PCR
Sample required: 4 – 5 ml. Whole blood.
Run days at section: Alternate day
Reported on: 3rd Working Day if received before 1400 Hrs

  • Test: Checq – B HBV DNA Qualitative PCR HBsAg and Anti HBc IgM Antibody combo panel

The technique used: Real Time PCR & CLIA
Sample required: 4 – 5 ml. Whole blood.
Run days at section: FOR PCR: Alternate day, FOR CLIA: Everyday
Reported on: 3rd Working Day if received before 1400 Hrs

  • Test: HCV Ampliq HCV RNA Qualitative PCR

The technique used: Real Time RT – PCR
Sample required: 4 – 5 ml. Whole blood submitted.
Run days at section: Alternate day
Reported on: 3rd Working Day if received before 1400 Hrs

  • Test: Checq – C HCV RNA Qualitative PCR & Anti – HCV IgM Antibody combo panel

The technique used: Real Time RT – PCR & CLIA
Sample required: 4 – 5 ml. Whole blood.
Run days at section: FOR PCR: Alternate day, FOR CLIA: Everyday
Reported on: 3rd Working Day if received before 1400 Hrs

  • Test: Tracq – C HCV RNA Quantitative PCR

The technique used: Real Time RT – PCR (Quantitative)
Sample required: 4 – 5 ml. Whole blood.
Run days at section: Alternate day
Reported on: 3rd Working Day if received before 1400 Hrs

  • Test: Tracq – C Duo HCV RNA Quantitative & HCV Genotyping Combo Panel

The technique used: Real Time RT- PCR (Quantitative) & RT – PCR, Linear Array
Sample required: 4 – 5 ml. Whole blood.
Special instruction: overnight fasting (10 – 12 Hrs.)
Run days at section: Alternate day
Reported on: 3rd Working Day if received before 1400 Hrs