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- Cancer HOT SPOT Panel – 50 Genes by NGS
- Cell-free or Circulating Tumour DNA (ctDNA)
- Circulating Tumor Cells
- Foundation one (solid tumors)
- PD – L1 TESTING
- BRCA 1 & 2
- Lung Cancer -ROS 1 Gene & Met Gene
- Panorama Test
- Syndrome Evaluation System
- MammaPrint Test
- Myeloproliferative Leukemia (MPL) Mutation Analysis
- Calreticulin Mutation
Cell-free or Circulating Tumour DNA (ctDNA)
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- Cell-free or circulating tumour DNA (ctDNA) is tumor DNA circulating freely in the blood of a cancer patient.
- Originates from dying tumour cells and can be present in a wide range of cancers but at varying levels and mutant allele fractions.
clinical Utility
- Qualitative and quantitative testing of circulating cell free DNA (CCFDNA) can be applied for the management of malignant and benign neoplasms.
- Detecting circulating DNA in cancer patients may help develop a DNA profile for early stage diagnosis in malignancies.
- To look for resistance mutation T790M in EGFR positive patients.
- Address the tumor heterogeneity.
Benefits
- It is non invasive
- Can be a substitute for primary biopsy in sick patients
- Repeated blood samples are much easier to obtain