Technical Notes

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ComboQuest Panels


Every technique is best within its advantages when applied for suitable assays. At OncQuest, we best utilize advantage & limitation characteristics to choose the suitable assay & technique. ComboQuest panels are an application of techniques in the matrix of sensitivity, specificity to brig you the maximum information about the patients disease status.

Immunophenotyping & Conventional Karyotyping

The Panels establish basic Diagnosis & lineage with immunophenotyping, Subsequent to routine hematological findings. Karyotypy further assist to define known & unknown chromosomal abnormalities that are important in evaluation for prognosis.
  • Acute Leukemia Comprehensive Diagnostic Panel + Karyotyping
  • Acute Lymphoblastic Leukemia B cell + Karyotyping
  • Acute Lymphoblastic Leukemia T cell + Karyotyping
  • Acute Myeloid Leukemia Panel + Karyotyping
  • Lymphoma Diagnostic Panel + Karyotyping
  • Acute lymphoblastic Basic lineage Diagnostic Panel + Karyotyping
  • Acute Lymphoblastic leukemia Characterization Panel + Karyotyping
  • Comprehensive CLL Panel + Karyotyping
  • Conventional Karyotyping & Real Time RT PCR

Comprehensive CML Quest D

Establish primary diagnosis with karyotyping & baseline value for molecular monitoring. Allows one to detect & confirm Ph Hybrid & Q PCR establishes the base level quantification for subsequent monitoring with its advantage to pick up the variants of Philadelphia hybrid in micro (p230), minor (p190)& major (p210) blast crisis.

FISH & Real Time RT PCR

Comprehensive CML Quest MRD
Panel is useful in
  • FISH negative patients can be confirmed by PCR
  • Tagging patients either in Cytogenetic OR Molecular remission
  • Making decision on BMT by calculating log reduction status
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